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Low blood sugar: signs, causes and the 15-15 rule

A hypo is a blood sugar below 70 mg/dL. It comes on fast and it is easy to treat if you know how — and everyone who lives with someone on insulin should know how.

Published · Bahria Diabetes Center

In short

  • Low blood sugar means a reading below 70 mg/dL (3.9 mmol/L).
  • Treat it with 15 g of fast sugar — 3 teaspoons of sugar in water, or half a glass of juice or a regular cold drink — then check again after 15 minutes.
  • Chocolate, biscuits and mithai are too slow: their fat holds the sugar back.
  • Hypos mostly happen on insulin and on sulphonylureas such as gliclazide, glimepiride and glibenclamide. Frequent hypos mean the treatment needs changing.

What counts as low

The American Diabetes Association describes three levels. Level 1 is glucose below 70 mg/dL (3.9 mmol/L). Level 2, below 54 mg/dL (3.0 mmol/L), is serious and needs action straight away. Level 3 is any hypo in which the person needs someone else's help, whatever the reading.

The signs

Early signs: shaking, sweating, a fast heartbeat, hunger, feeling anxious or irritable, dizziness, and tingling around the lips. As the sugar falls further: confusion, blurred vision, clumsiness and odd behaviour — often mistaken for tiredness or bad temper — and, in severe cases, fits. At night, a hypo can show up as nightmares, crying out in sleep, or sweating.

Some people, especially after many years of diabetes or many hypos, stop feeling the early signs. This is called hypo unawareness, and it is a reason to review treatment.

What to do: the 15-15 rule

  • Check your sugar if you can. If it is below 70 mg/dL — or you feel a hypo coming and can't check — treat it.
  • Take 15 g of fast sugar: 3 teaspoons (one tablespoon) of sugar stirred into water, half a glass (about 120 ml) of juice or a regular cold drink — not diet — or glucose tablets.
  • Wait 15 minutes and check again. If it is still below 70, take another 15 g.
  • Once it is above 70, if your next meal isn't due soon, eat a snack with carbohydrate and protein — a roti with dahi, or a glass of milk.

Don't treat a hypo with chocolate, mithai or biscuits: the fat in them slows the sugar down. A tablespoon of honey works like sugar, except in a child under one.

If someone can't swallow

If the person is very drowsy, confused or unconscious, don't put food or drink in their mouth — they can choke. Lay them on their side and call Rescue 1122 or get them to hospital. Glucagon, an injection or nasal spray that raises sugar, can be given by family if it has been prescribed; the ADA advises that everyone on insulin has it and that the people around them know how to use it.

Why hypos happen

Almost always because of medicine: insulin, or tablets that push the pancreas to release insulin — the sulphonylureas gliclazide, glimepiride and glibenclamide. Metformin, DPP-4 inhibitors (the gliptins), SGLT2 inhibitors and GLP-1 medicines don't cause hypos on their own.

Then come the triggers: a missed or late meal, less roti than usual, more walking or exercise than usual, a dose taken twice by mistake, and kidney disease, which makes some medicines last longer. Fasting in Ramadan without adjusting doses is a common cause here.

After a hypo

A single hypo with an obvious cause — a skipped meal — needs only the cause fixed. Hypos that keep coming, happen at night, or needed someone else's help mean the treatment should be reviewed, often with lower doses or a change of medicine. The ADA counts a recent severe hypo as a major risk factor for the next one.

Don't drive while you have a hypo. If you take insulin or a sulphonylurea, check your sugar before you drive.

Common questions

What is the fastest way to raise low sugar at home?
Sugar dissolved in water — 3 teaspoons, one tablespoon — or half a glass of juice or a regular cold drink. Then check again after 15 minutes.
Can I use a diet drink or sugar-free sweets for a hypo?
No. Diet drinks and sugar-free sweets have no sugar in them, so they won't raise a low reading. Use ordinary sugar, juice or a regular cold drink.
Is honey good for a hypo?
Yes — one tablespoon works like sugar. Just not for a child under one year old.
Can low sugar happen without diabetes medicine?
Rarely. In someone who isn't taking insulin or a sulphonylurea, a truly low reading is unusual and should be investigated rather than treated at home — tell your doctor.

Sources

  1. American Diabetes Association Professional Practice Committee. 6. Glycemic goals, hypoglycemia, and hyperglycemic crises: Standards of Care in Diabetes—2026. Diabetes Care 2026;49(Suppl 1):S132–S149. doi.org/10.2337/dc26-S006
  2. American Diabetes Association. Low blood glucose (hypoglycemia): symptoms and treatment. diabetes.org/living-with-diabetes/hypoglycemia-low-blood-glucose/symptoms-treatment
  3. American Diabetes Association. Hypoglycemia (low blood glucose): the 15-15 rule. diabetes.org/living-with-diabetes/treatment-care/hypoglycemia
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